ING4 and anti-neutrophil cytoplasmic antibody-associated vasculitis: Based on the reduced ING4 expression in leukocytes from anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) patients and the acetylation of histone H4K16 modified by complexes containing ING4, Yang et al. [169] suggested that the epigenome may be involved in AAV pathogenesis.