Although we could not detect significant amounts of HGF in media from fresh CLL B cells cultured for 72 h, we instead found higher HGF levels in sera from CLL patients than in sera from normal controls (mean in CLL 932 ± 315 pg/mL, n = 10, vs mean in healthy controls, 601 ± 46 pg/mL, n = 3) as already reported [60,61]. Here, HGF is linked to B-cell chronic lymphocytic leukemia.