As it was published before, a scattered TP53 staining (using the diagnostic antibody clone Bp53-11 [28]) is related with normal (wild-type) genetic background with no p53 mutations [30], while no staining or increased (over 66% of tumor cells stained) staining pattern is related with “altered”, frequently even mutated p53 [30]. The gene discussed is TP53; the disease is neoplasm.