As previously reported [8], female and male IL-10 mutant mice succumbed to whipworm infection between day 19 and 24 p.i., showing a dramatic weight loss and high numbers of worms in the caecum when compared with WT mice (Fig 1A). Similarly, female and male IL-10Rα mutant mice displayed weight loss and all required euthanasia by day 28p.i. Here, IL10RA is linked to trichuriasis.