Similarly, T. muris-infected IL-10 and IL-10Rβ mutant mice presented a clear and consistent overgrowth of Enterobacteriaceae, Escherichia/Shigella and Enterococcus (S9 and S11 Figs). The degree of colonization by these pathobionts correlated with the reduced survival (time after infection that mice succumbed) and extent of liver disease observed (S12 Fig). Here, IL10 is linked to liver disorder.