Several researches had shown that the proliferation and survival of T-ALL cells depended on cytokines, such as IL-2, IL-4, IL-8, IL-9, and IL-15 [29–32] In this study, the concentration of IL-2 in CD59-overexpressing Jurkat cell cultures was increased by ELISA compared to normal Jurkat cells. This evidence concerns the gene IL4 and acute lymphoblastic leukemia.