Examples include associations of SNPs corresponding to ABCB9 with college completion and years of education, ATG10 with vascular dementia, C9orf72 with amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and response of rheumatoid arthritis patients to anti-TNF treatment, GNAI3 with total and low-density lipoprotein cholesterol (LDL-C) and major depression, LPXN with inflammatory bowel disease, MED30 with rheumatoid arthritis and fasting blood glucose, PRDM10 with type 2 diabetes, and SFN with high-density lipoprotein cholesterol (HDL-C) [43]. This evidence concerns the gene TNF and major depressive disorder.