CSPG4 and acute lymphoblastic leukemia: When equal numbers of NG2+ and NG2− B-ALL primary blasts (105 cells/patient, n = 4) were intravenously (i.v.)infused into NSG mice, engraftment levels after 8 weeks were 3.5-fold higher in the PB of mice transplanted with NG2+ than in equivalent mice transplanted with NG2− blasts (11.2 ± 1.8% vs. 3.2 ± 1.5%, p = 0.008) (Fig. 1a, left and middle panels).