Similar data were obtained in the setting of adoptive transfer of CD73+/− OT-II or CD73−/− OT-II CD4+CD25- naïve T cells (CD90.2+) into B16-OVA-bearing mice (CD90.1+) for examining the tumor antigen-specific Treg conversion (Supplementary Fig. 6B), consistent with the previous results25–27. Here, CD4 is linked to neoplasm.