We found that there was almost no changes in serum ALT, AST and TBIL in mice 24 h, 48 h, and 72 h after HYX1 transplantation alone, compared with normal mice (Additional file 1: Figure S4). The results of present study showed that HYX1 cell transplantation provides a protective effect against ConA-induced acute liver injury. Here, GPT is linked to injury.