Older age, female sex, obesity, diabetes, renal insufficiency, pre-ECMO blood lactate, elevated CK-MB levels, low serum albumin level, low platelet count, poor cardiac systolic function, and logistic EuroSCORE more than 20% were independently associated with in-hospital death in PCS patients undergoing ECMO after cardiac-related procedures [1, 2, 7, 9, 11, 27–31]. The gene discussed is ALB; the disease is obesity due to melanocortin 4 receptor deficiency.