IL24 and prostate neoplasm: We demonstrated, by delivering a replication-deficient or a conditionally replication-competent adenovirus expressing the pro-apoptotic gene mda7/interleukin-24 enclosed in microbubble and in combination with ultrasound, that we could achieve sustained expression of the transgene in the sonoporated region and induce a reduction or complete eradication of a human prostate tumor xenograft [21].