CD274 and non-small cell lung carcinoma: Results from this preclinical study are in line with the clinical benefit observed in a phase III clinical trial (IMpower150) in which the PD-L1 antibody atezolizumab was combined with bevacizumab and chemotherapy (the carboplatin and paclitaxel doublet) in metastatic NSCLC patients, compared to patients treated with bevacizumab plus chemotherapy (NCT02366143) [80].