In our study, the levels of 13 glycerophospholipids (1 lyso-PC and 12 PCs) and 9 glycerophospholipids (2 lyso-PC and 7 PCs) were observed to be significantly lower in the upper serum Hp tertile group than in the lower tertile group in T2DM patients and non-DM subjects, respectively. This evidence concerns the gene HP and diabetes mellitus.