Genes with vascular and/or glial cell function emerged from investigating syndromes in which migraine is prevalent, such as NOTCH3 in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) and CSNK1D in familial advanced sleep phase syndrome (FASPS). This evidence concerns the gene CSNK1D and Familial advanced sleep-phase syndrome.