Figure 6A shows that T1 resulted in G2/M cell cycle arrest in cancer cell lines. In contrast, the arrest in hTERT-HPNE cells was only observed at 50 μM T1. Consistent with these findings, the expression of cyclinB1 and cdk1 proteins in cancer cells was significantly increased after treatment with T1 complex for 24 h and 48 h (Figure 6B). The gene discussed is CDK1; the disease is cancer.