DNA methylation array data for 35 lung adenocarcinoma (LADC) and 26 healthy lungs from the Cancer Genome Atlas (TCGA) indicated that the methylation index of two probes mapped to LDOC1 CpG islands were significantly increased in LADC samples compared with healthy lung tissue (p = 0.001024 and 0.045721, respectively; Figure 1E). This evidence concerns the gene LDOC1 and lung adenocarcinoma.