Patient 2, who developed an invasive ductal carcinoma (estrogen, progesterone and HER2/neu positive staining, tumor size pT1a, grade II, pN0/1sn) at the age of 31 years and showed hypermethylation exceeding the threshold by +0.05 at RAD51C, was also evaluated for promoter methylation in the tumor tissue. Here, ERBB2 is linked to neoplasm.