The flow cytometry analyses of ADPKD (vs. non‐ADPKD) tissues revealed increased numbers of intrarenal CD3 T cells (0.500 vs. 0.081 percent of total renal cells; P = 0.006; Fig. 2) as well as their subtypes: CD4 T helper cells (0.189 vs. 0.034; P = 0.014), CD8 cytotoxic T cells (0.249 vs. 0.043; P = 0.008), and double negative (DN) T cells (0.041 vs. 0.004; P = 0.070). Here, CD4 is linked to autosomal dominant polycystic kidney disease.