Analysis of the lipid composition of membrane Hsp70-positive (mHsp70) tumor cells revealed that globoyltriaosylceramide (Gb3), which is residing in cholesterol-rich microdomains of tumor but not normal cells, serves as a potential binding partner for mHsp70 (Gehrmann et al. 2008; Simons and Toomre 2000; Nimmervoll et al. 2015). The gene discussed is HSPA1A; the disease is neoplasm.