This study assessed the association of tag and well-studied SNPs (APOA1 rs5072, APOC3 rs5128, APOA4 rs5104, APOA5 rs651821, ZPR1 rs2075294 and BUD13 rs10488698) selected from the Han Chinese data in Haploview (http://hapmap.ncbi.nlm.nih.gov/) and based on previous studies (Wu et al., 2015, 2016) with dyslipidemia in the overall sample and stratified by genders in a large sample from a Han Chinese population. Here, APOA1 is linked to metabolic syndrome.