We highlight 2 examples of CpGs, which are implicated by all 4 analyses: cg23161492 in ANPEP (a gene previously identified in the GWAS of Type 2 diabetes69 and implicated in major depressive disorder by pathway analysis70) and cg04907244 in SNORD93, a snoRNA that was previously reported as a potential early diagnostic marker of Alzheimer’s disease because it was found to be differentially expressed in juvenile cortices of a mouse model for Alzheimer’s disease.71 Both CpGs were also associated with gene expression levels in cis in blood (Supplemental Table 7). This evidence concerns the gene ANPEP and major depressive disorder.