Karikoski et al. also showed that stabilin-1−/− mice presented with smaller primary and metastatic tumors than WT mice (231) and these findings were corroborated with preliminary data in human HCC tissues ex vivo, which has shown that stabilin-1 expression is highly augmented in peritumoural endothelia and correlated with adverse histological features (233). The gene discussed is STAB1; the disease is metastatic neoplasm.