CDC42 and neoplasm: The results showed that the expressions of total CDC42 were relatively stable, but CDC42GTP were significantly decreased in SW620.W tumor group compared to the SW620.veh control tumor group (p < 0.05), While CDC42GTP was increased in SW480.shW tumor group compared to SW480.SCR tumor (only one tumor grew out of five mice, no statistics) (Fig. 2i, j, Supplement Fig. 3e).