Directly applying resistin to chondrosarcoma cell lines (JJ012 and SW1353) promoted mRNA and VEGF-A protein expression in a concentration-dependent manner (Fig. 1a, b), while stimulating chondrosarcoma cell lines with resistin (30 ng/ml) facilitated VEGF-A expression in a time-dependent manner (Fig. 1c, d). Here, RETN is linked to chondrosarcoma.