The phenotypic intersection between Stargardt disease and PD is also apparent from a histopathological study of a PRPH2 p.Cys213Tyr PD donor eye, finding that RPE cells were distended with lipofuscin much in an analogous manner to donor eyes with defective ABCA4 (Zhang et al. 2002). This evidence concerns the gene PRPH2 and Stargardt disease.