BCL2 and breast carcinoma: Our results are relatively close to those reported in human breast cancer studies in terms of frequency of Bcl-2 expression: at 10% threshold for positivity, Bcl-2 is expressed in 68.2% of the 7230 human invasive mammary carcinomas according to the large-scale study by Hwang et al. [9] in comparison to 52.2% in our study.