Enrichment of coding non-synonymous PPP1R3B variants having a MAF < 0.1% was also observed using the http://www.type2diabetesgenetics.org, where 51 carriers out of 9,121 patients with diabetes were found in contrast to 40 carriers out of 9,335 non-diabetic individuals [30]. Here, PPP1R3B is linked to diabetes mellitus.