Also a significantly higher level of plasma LDL-cholesterol was found among diabetic carriers (3.40 mmol/L (IQR: 2.6–3.9)) of rare PPP1R3B missense variants compared to patients with T2D without such variants (2.20 mmol/L (IQR: 1.80–2.90), (p = 0.008)) (Tables 2 and 3). Here, PPP1R3B is linked to type 2 diabetes mellitus.