Upstream effectors of this signaling cascade include deregulation of the TGF‐β pathway, increased in T2DM patients (Qiao et al., 2017) and described as a CC oncogene (Xu and Pasche, 2007); and Wnt activation, postulated as a possible link between diabetes and cancer (García‐Jiménez et al., 2014). This evidence concerns the gene TGFB1 and type 2 diabetes mellitus.