Many evidences suggested a role in cancer initiation of the protein complex YAP/TAZ‐TEAD (Zanconato et al., 2016) including several signaling pathways that we found altered in normal diabetic mucosa: MAPK (Hong et al., 2014), VEGF (X. Wang et al., 2017), Wnt (Konsavage et al., 2012), TGF‐β (Hiemer et al., 2014), or the Notch pathway (Slemmons et al., 2017). This evidence concerns the gene VEGFA and cancer.