Moreover, FGF23 excess also leads to several congenital hypophosphatemic diseases, such as autosomal dominant hypophosphatemic rickets (ADHR: OMIM #193100) (ADHR Consortium, 2000) and X-linked hypophosphatemia (XLH; OMIM #307800) (The HYP Consortium, 1995). This evidence concerns the gene FGF23 and X-linked hypophosphatemia.