In univariate analysis (Table 3), the location of tumor (P = 0.034), low degree of pathological differentiation (P = 0.010), CA199≥40U/ml (P = 0.009), serum albumin<40g/L (P = 0.002), LDH≥225 U/L (P = 0.038), and LDH≥225 U/L combined with SLA≥4.0 mmol/L (P = 0.018) were identified as poor prognostic factors for the PFS of patients with mCRC. Here, ALB is linked to neoplasm.