A logistic regression model including the variables of sex, age, and genotypes showed that the mutated genotypes LTA +252 (AG+GG), TNFA −857 (CT+TT), and TNFA −238 (GA+AA) remained risk factors only for the development of the paranoid form of schizophrenia (p = 0.001/OR = 2.6, p = 0.0002/OR = 3.2, and p = 0.0004/OR = 3.1, respectively). This evidence concerns the gene TNF and schizophrenia.