Finally, Apo A1/Apo B ratio in the aerobic exercise group insignificantly increased after the intervention compared with the pre-intervention, and its average changes were not significant in comparison with those of the control group; therefore, it could be argued that doing exercises in patients with COPD cannot prevent the predisposition of cardiovascular diseases through affecting lipid profiles. The gene discussed is APOB; the disease is chronic obstructive pulmonary disease.