Stress response also includes the release of prolactin, which is of significant clinical relevance as there is substantial evidence that prolactin plays a significant role in the development of stress-induced pathology, including stress-induced intestinal epithelial barrier dysfunction [25], stress-induced tracheal epithelial barrier dysfunction [26], cardiac dysfunction in peripartum cardiomyopathy [27], and psychological stress in the development of cardiovascular pathology [28]. This evidence concerns the gene PRL and peripartum cardiomyopathy.