Gonadotroph and nonfunctioning pituitary adenomas had the highest mean SSTR4 expression (both 1.64, 95% CI 1.02–2.25 and 1.31–1.98, respectively) followed by PIT-1-positive adenomas (1.44, 95% CI 0.97–1.91). This evidence concerns the gene SSTR4 and adenoma.