The patient was treated with Ruxolitinib, which is a tyrokinase inhibitor of Jak phosphorylation (thus indirectly preventing Stat-1 hyperphosphorylation in the patient) for 6 months; following this treatment, a restitution of IL-17 production was observed with general systemic health improvement but only a partial improvement in oral candidiasis (29). The gene discussed is STAT1; the disease is oral candidiasis.