In the bivariate meta-GWAS analysis with schizophrenia, 16 loci reached bivariate genome-wide significance of which 10 replicated (ZNF804A, ITIH3, FHIT, MIR3143, PSORS1C2, STK19, SPATA31D1, RTN1, BAG5, TCF4) and 6 did not (MATN1, AGBL4, VPS45, TSNARE1, CACNA1C, ZCCHC14) (Fig. 1d, Table 1, Supplementary Table 1, Supplementary Figure 1). This evidence concerns the gene BAG5 and schizophrenia.