INS and myeloid sarcoma: Fatigue [33,34,39]; weight [34]; inflammation and regulation of immune system by insulin (due to sugar) and artificial sweeteners, candida overgrowth leading to leaky gut syndrome [30]; development of MS [48]; increase uric acid, which increases inflammation [48]; aspartame metabolizes to methanol, which is a potent neurotoxin [48]; artificial sweeteners can irritate bladder [39]; sugary snacks can cause energy crash [39]