In the discovery process, two particular genes stand out with high hazard ratio (HR) and concordance index (CI) in univariate Cox model, AQP1 (HR = 3.3, p < 0.05, CI = 0.711) and MEOX2 (HR=2.5, p < 0.05, CI = 0.675), both of which are lesser known to be associated with survival in gliomas. Here, AQP1 is linked to central nervous system cancer.