IFNAR1 and infection: Other flaviviral encephalities are being studied using this mouse model of infection, as that caused by Langat encephalitis virus (LGTV), showing type I IFN as a critical factor to control LGTV infection, as LGTV RNA was found in all organs in the absence of IFNAR, whereas in wild-type mice only low viral burdens can be detected in the olfactory bulb [114,115].