Many genes which co-express with A3B amongst most tumour types are known to be involved in processes such as cell cycle regulation (CDC25C, FOXM1), DNA replication (CDC6, CDC45) and the maintenance of the mitotic spindle (AURKB, CDCA5, CDCA8), while the examination of some immune markers shows clear correlation of their expression with that of A3G and A3H, but not with A3B (Supplementary Figure S18). This evidence concerns the gene APOBEC3B and neoplasm.