GPT and Fever: In study part 2, the most frequently reported treatment-related TEAEs were constipation, malaise, hiccups, and increased bilirubin (all with an incidence of 9.7%; 3/31), followed by nausea, vomiting, pyrexia, hypoalbuminemia, increased aspartate aminotransferase (AST), and increased alanine aminotransferase (ALT; all with an incidence of 6.5%; 2/31) (Table 2).