Methods: We recruited 164 infants (age < 6 months) hospitalized for bronchiolitis in this study and determined TLR5 rs5744174 (C > T) single nucleotide polymorphism, virus etiology and severity markers of bronchiolitis, and presence of post‐bronchiolitis asthma until age 11 to 13 years. Here, TLR5 is linked to bronchiolitis.