In previous studies, the SCS prevalence was reported to be 5% to 20% in patients with adrenal incidentalomas.28 Because in our study, some of the patients with an adrenal mass were followed up by other clinics and serum cortisol, ACTH and 24‐hour urine cortisol values of these patients could not be obtained, we think that the number of patients with SCS might possibly be higher than the rate identified (0.9%). The gene discussed is POMC; the disease is adrenal cortex adenoma.