Based on its angiogenic function, FGF1 is a major player in wound healing [67, 68]; it has decreased gene expression in early phases of wound healing in diabetic patients [69], and it has a proven effect on reepitelization in NONcNZO10/LtJ mouse (model for impaired wound healing in type 2 diabetes) [70]. This evidence concerns the gene FGF1 and type 2 diabetes mellitus.