Daidzin downregulated VEGF and eNOS protein expression, and apigenin intervention increased VEGF and eNOS protein levels (P < 0.001), but did not reverse the effect of Daidzin, and the protein expression at 7 d was higher after cerebral ischemia than that at 14 d in all the model groups (P < 0.05), which was similar to the Caveolin-1 expression (Figures 4(h)–4(k)). This evidence concerns the gene NOS3 and brain ischemia.