According to the RT-qPCR results, the expression levels of LncRNA-HEIH and LncRNA-HULC were significantly upregulated in the peripheral blood of HBV-positive patients (HBV, HBV + HC, and HBV + HCC groups), as compared to the control group (p < 0.05, Figure 1(a)). The gene discussed is HULC; the disease is hepatocellular carcinoma.