POU4F3 (NM_000307.4), known for causing recessive X-linked HL, was found to be mutated in Sporadic Case_9 (c.989G>A, p.(Arg330Lys) and Sporadic Case_14 (c.967C>G, p.(Arg323Gly) (Table 1). The gene discussed is POU4F3; the disease is Hodgkins lymphoma.