Asthma is characterized by an expansion of CD4+ helper T lymphocytes (Th2, Th17), increased production of the Th2 cytokines IL-4, IL-5, and IL-13, an increased level of allergen-specific immunoglobulin E (IgE), eosinophilia and inflammation of the airways (37). This evidence concerns the gene IL4 and Increased total eosinophil count.