CXCL12 and rheumatoid arthritis: Since the dysregulated expression of SDF-1/CXCR4 is associated with the pathology of various autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, and multiple sclerosis, targeting SDF-1/CXCR4 axis with 4-F-Benzoyl-TN14003 may be beneficial for prevention of autoimmune disease (198–201).