In women with endometriosis, persistence of proliferative markers in eutopic endometrial cells seemed to be associated with virtually complete loss of γ-H2AX (36); and endometrial cells from ectopic sites dysplayed immune-staining for proliferative markers, with concomitant loss of the γ-H2AX staining in ectopic endometriotic lesions of both human and baboon endometriosis model (37). This evidence concerns the gene H2AX and endometriosis.